Results CGRP has significant preventive and protective effect to focal cerebral infarction which showed the nervous system scores took a favourable turn, brain edema descended and infarction volume reduced. This effect was related with the dose and the way of administration of CGRP. 结果CGRP对鼠局灶性脑梗死有明显的预防和保护作用,表现为神经系统评分好转,脑水肿减轻,梗死体积减小,而这种作用与给药时间、给药剂量和方式有关。
Objective To study the effect and mechanism of blood-brain barrier ( BBB) permeability after focal ischemia in rats by intracarotid infusion of low dose bradykinin. 目的研究颈动脉灌注小剂量缓激肽对缺血后血脑屏障通透性的影响及机制。
Objective To investigate the protective role of transient focal ischemic precondition ( PC) against permanent focal cerebral ischemia, to define the proper time dose for precondition, and to study the reaction of astroglia in cerebral ischemic tolerance. 目的研究短暂性局灶性脑缺血预处理对永久性局灶性脑缺血的保护作用,及最佳预处理时间剂量,并探讨星形胶质细胞在脑缺血耐受中的反应。
Results KNT could alleviate volume of cerebral infarct caused by focal cerebral ischemia in a dose-dependent manner and improve neurological symptoms. 结果抗脑血栓片可依剂量性减轻大鼠局灶性脑缺血所致的脑梗塞体积以及改善由脑缺血引起的神经症状。